Our work is entirely funded by private donations – we receive no money from government. Your money will help us continue funding research into vitiligo and supporting people affected by the condition.
229 listed sites: Australia (11); Belgium (5); Bulgaria (14); Canada (23); China (22); Germany (12); Hungary (8); Italy (7); Japan (10); Mexico (5); Poland (11); Puerto Rico (3); Slovakia (8); Spain (12); Taiwan (5); Turkey (Türkiye) (2); United Kingdom (3); United States (68) - 08 Nov `23Ritlecitinib for nonsegmental vitiligo
Ritlecitinib for nonsegmental vitiligo
Official title: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, 52-WEEK PLACEBO-CONTROLLED MULTI-CENTER STUDY WITH A DOUBLE-BLIND 52-WEEK EXTENSION PERIOD WITH RANDOMIZED DOSE UP/DOSE DOWN TITRATION INVESTIGATING THE EFFICACY, SAFETY, AND TOLERABILITY OF RITLECITINIB IN ADULT PARTICIPANTS WITH NONSEGMENTAL VITILIGO
Status: Closed to new participants
Description:
Pfizer enrolled about 1,571 participants. Ritlecitinib is an oral immune-modulating drug that blocks JAK3 and TEC-family signaling. Researchers hope it will reduce the immune attack on melanocytes and support repigmentation. Ritlecitinib is sold as Litfulo and is approved for severe alopecia areata in people age 12 and older; vitiligo would be a new use. Possible effects include headache, diarrhea, acne, and infections. People age 18 and older may qualify. The study is underway but is no longer accepting new participants.
Start date: November 08, 2023
Completion date: July 30, 2027
Organizer: Pfizer
Contact: Pfizer CT.gov Call Center
Clinical Trial Alerts
Sign up and be the first to know about updates on this trial.
FAQOther Questions
- Is there a link between vitiligo and depression?
Depression and anxiety are often linked with vitiligo, significantly impacting a person’s quality of life. The connection stems from the shared origin of the skin and brain duri...
- Is vitiligo contagious?
Vitiligo is not contagious. This means it cannot be spread from person to person through physical contact, sharing personal items, or any other means of transmission. Vitiligo i...
- What are risks of oral and topical corticosteroids?
Corticosteroid drugs (like hydrocortisone, and others) are often used for treating vitiligo. By mimicing the effects of hormones your body produces naturally in your adrenal gla...
Though it is not always easy to treat vitiligo, there is much to be gained by clearly understanding the diagnosis, the future implications, treatment options and their outcomes.
Many people deal with vitiligo while remaining in the public eye, maintaining a positive outlook, and having a successful career.
Copyright (C) Bodolóczki JúliaBy taking a little time to fill in the anonymous questionnaire, you can help researchers better understand and fight vitiligo.