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Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo
Description:
This study aims to investigate the role of Hypoxia Inducible Factor (HIF) and autophagy-related genes in the pathogenesis of vitiligo among Egyptian patients in the Sohag Governorate. It will explore the presence of HIF, defects in autophagy-related genes, and their cross-interaction in vitiligo. A control group of participants without vitiligo will also be included for comparison.
Key Details
- Age Range: 18 to 75 years
- Study Population: Patients with non-segmental vitiligo and a healthy control group
Inclusion Criteria
- Adults aged 18 years and older
- Diagnosed with non-segmental vitiligo
- Control group participants without vitiligo
Exclusion Criteria
- Pregnant individuals
- Patients with chronic inflammatory skin disorders
- Use of antioxidants or anti-inflammatory drugs
- Recent topical or systemic vitiligo treatment (within the last 4 weeks)
- Presence of other autoimmune diseases or diabetes mellitus
Location: Sohag, Egypt
For a complete list of inclusion and exclusion criteria, interested individuals should contact the study team or visit the official ClinicalTrials.gov page (NCT06410898). Only the research staff can determine if a person fully qualifies for the study.
Start date: April 25, 2024
Completion date: July 25, 2024
Contact: Rania H Metwally
Tel.: 01018845428
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